PUM2 anticorps (AA 901-1066)
Aperçu rapide pour PUM2 anticorps (AA 901-1066) (ABIN1714224)
Antigène
Voir toutes PUM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 901-1066
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Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human Pumilio 2
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))
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Autre désignation
- Pumilio 2
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Sujet
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Synonyms: FLJ36528, KIAA0235, MGC138251, MGC138253, PUM 2, Pum2, PUM2, PUMH2, Pumilio Drosphila homolog 2, Pumilio homolog 2 Drosophila, Pumilio homolog 2, Pumilio2, PUM2_HUMAN.
Background: Pumilio 2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding mRNA targets. It supports proliferation and self-renewal of stem cells by regulating the translation of key transcripts. The Pumilio gene encodes proteins that are required for development of germ stem cells in one or both sexes. The Pumilio protein interacts with the human Nanos1 protein and this interaction may play a conserved role in germ cell development. Pumilio 2 is highly expressed in testis and ovary and at lower levels in brain, heart, kidney, liver, muscle, placenta, intestine and stomach. It is also expressed in stem cells, germ cells and in most fetal tissues.
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ID gène
- 23369
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Antigène
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