CLP1 anticorps (AA 1-100)

N° du produit ABIN1714385

L’anticorps Lapin Polyclonal anti-CLP1 a été validé pour WB, ELISA, IF (cc), IF (p), IHC (p), ICC et IHC (fro). Il convient pour détecter CLP1 dans des échantillons de Humain.

Aperçu rapide pour CLP1 anticorps (AA 1-100) (ABIN1714385)

Antigène: CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CLP1 anticorps

Épitope: AA 1-100

Homologie: Human,Mouse,Rat,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HEAB

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CLP1

Antigène: CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))

Autre désignation: HEAB

Sujet:

Synonyms: ATP/GTP binding protein, CLP 1, clp1, CLP1 cleavage and polyadenylation factor I subunit homolog, CLP1, cleavage and polyadenylation factor I subunit, homolog S. cerevisiae, CLP1, yeast, homolog of, CLP1_HUMAN, hClp1, Homolog of yeast CFIA subunit Clp1p, Polynucleotide kinase Clp1, Pre mRNA cleavage complex II protein Clp1, Pre-mRNA cleavage complex II protein Clp1.

Background: HEAB is a 425 amino acid nuclear protein that belongs to the Clp1 family. Utilizing magnesium, manganese or nickel as cofactors, HEAB participates in the phosphorylation of the 5'-hydroxyl groups of double- and single- stranded RNA and DNA. HEAB is a member of the tRNA splicing endonuclease complex, in conjunction with TSEN2, TSEN15, TSEN34 and TSEN54, and is also a member of the pre-mRNA cleavage complex II. The gene encoding HEAB maps to human chromosome 11q12.1 and mouse chromosome 2 D, mutations to this gene may lead to a reduced pre-mRNA cleavage activity. HEAB exists as two isoforms due to alternative splicing events.

ID gène: 10978

Pathways: Ribonucleoprotein Complex Subunit Organization