CLP1 anticorps (C-Term)
-
- Antigène Voir toutes CLP1 Anticorps
- CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))
-
Épitope
- AA 308-336, C-Term
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp CLP1 est non-conjugé
-
Application
- Western Blotting (WB)
- Homologie
- B, C, Pr, M, Rat
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This CLP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-336 amino acids from the C-terminal region of human CLP1.
- Clone
- RB37304
- Isotype
- Ig Fraction
- Top Product
- Discover our top product CLP1 Anticorps primaire
-
-
- Indications d'application
- WB: 1:1000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- CLP1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Date de péremption
- 6 months
-
- Antigène
- CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))
- Autre désignation
- CLP1 (CLP1 Produits)
- Synonymes
- anticorps Heab, anticorps RGD1307679, anticorps AI462438, anticorps ACDP1, anticorps CLP-1, anticorps CGP-39, anticorps GP-39, anticorps SPC-40, anticorps SPS-40, anticorps YKL-40, anticorps HEAB, anticorps hClp1, anticorps fa28a12, anticorps wu:fa28a12, anticorps clp1, anticorps cleavage and polyadenylation factor I subunit 1, anticorps CLP1, cleavage and polyadenylation factor I subunit, anticorps cyclin and CBS domain divalent metal cation transport mediator 1, anticorps chitinase 3-like 1 (cartilage glycoprotein-39), anticorps cleavage and polyadenylation factor I subunit 1 L homeolog, anticorps Clp1, anticorps CNNM1, anticorps CHI3L1, anticorps CLP1, anticorps clp1, anticorps clp1.L
- Sujet
- Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing, this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.
- Poids moléculaire
- 47646
- ID gène
- 10978
- NCBI Accession
- NP_001136069, NP_006822
- UniProt
- Q92989
- Pathways
- Ribonucleoprotein Complex Subunit Organization
-