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Inversin anticorps (AA 31-130)

INVS Reactivité: Humain, Souris WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1714386
  • Antigène Voir toutes Inversin (INVS) Anticorps
    Inversin (INVS)
    Épitope
    • 14
    • 5
    • 1
    • 1
    AA 31-130
    Reactivité
    • 22
    • 15
    • 1
    Humain, Souris
    Hôte
    • 21
    • 1
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Inversin est non-conjugé
    Application
    • 18
    • 12
    • 12
    • 8
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Cow,Sheep,Chimpanzee
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Inversin
    Isotype
    IgG
    Top Product
    Discover our top product INVS Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Inversin (INVS)
    Autre désignation
    Inversin (INVS Produits)
    Synonymes
    anticorps invs-a, anticorps INVS, anticorps MGC140477, anticorps inv, anticorps NPH2, anticorps NPHP2, anticorps INV, anticorps Nphp2, anticorps RGD1563359, anticorps wu:fe47e11, anticorps inversin S homeolog, anticorps inversin, anticorps Inversin, anticorps invs.S, anticorps INVS, anticorps Bm1_38710, anticorps PTRG_09181, anticorps EAMY_RS33690, anticorps LOAG_11716, anticorps invs, anticorps Invs
    Sujet

    Synonyms: INV, Inversion of embryo turning homolog, inversion of embryonic turning, INVS, Nephrocystin 2, Nephrocystin-2, Nephrocystin2, nephronophthisis 2 infantile, NPH2, NPHP2, INVS_HUMAN.

    Background: Nephrocystin-2 is a 1,065 amino acid protein that exists as three alternatively spliced isoforms and is essential for establishment of the left-right axis and normal renal development. Localizing to the cytoplasm, cytoskeleton, membrane and nucleus, nephrocystin-2 is expressed during presomite-stage embryos and persists in adulthood, with high levels of expression in liver and kidney. Mice expressing nephrocystin-2 mutations are primarily generated by random insertional mutagenesis and result in the reversal of left/right polarity and cyst formation in the kidneys. Furthermore, altered nephrocystin-2 function reverses nodal and lefty expression, indicating that nephrocystin-2 signaling occurs upstream of these proteins involved in the development of asymmetry.

    ID gène
    27130
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