BCL2L1 anticorps (pThr47)

N° du produit ABIN1714412

L’anticorps Lapin Polyclonal anti-BCL2L1 a été validé pour WB, ELISA, IHC (p), ICC, IF (cc), IF (p) et IHC (fro). Il convient pour détecter BCL2L1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BCL2L1 anticorps (pThr47) (ABIN1714412)

Antigène: BCL2L1 (BCL2-Like 1 (BCL2L1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL2L1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-BCL2L1 anticorps

Épitope: pThr47

Réactivité croisée: Humain, Souris, Rat

Homologie: Cow,Sheep,Pig,Horse,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human BCL2L1 around the phosphorylation site of Thr47

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur BCL2L1

Antigène: BCL2L1 (BCL2-Like 1 (BCL2L1))

Autre désignation: Bcl-xL/BCL2L1

Sujet:

Synonyms: BCL2L1 phospho T47, BCL2L1 phospho Thr47, p-BCL2L1 phospho T47, p-BCL2L1 Thr47, p-BCL2L1Thr115, Apoptosis regulator Bcl X, BclX, Bcl-X, Bcl 2 like 1, Bcl 2 like 1 protein, Bcl xL, BCL X/L, BCL XL/S, Bcl xS, Bcl2 like1, BCL2-related gene, BCL2-related protein, long isoform, included, BCLXL, included, BCL2-related protein, short isoform, included, BCLXS, included, BCL2L, BCL2L1, Bclx, DKFZp781P2092, MGC113803, MGC99998, B2CL1_HUMAN.

Background: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008].

ID gène: 598

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling