ADRM1 anticorps (AA 21-120)

N° du produit ABIN1714487

L’anticorps Lapin Polyclonal anti-ADRM1 a été validé pour ELISA, IF (cc), IF (p), IHC (p), ICC et IHC (fro). Il convient pour détecter ADRM1 dans des échantillons de Humain.

Aperçu rapide pour ADRM1 anticorps (AA 21-120) (ABIN1714487)

Antigène: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRM1 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-ADRM1 anticorps

Épitope: AA 21-120

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ADRM1

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ADRM1

Antigène: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Autre désignation: ADRM1

Sujet:

Synonyms: 110 kDa cell membrane glycoprotein, adhesion regulating molecule 1, Adhesion-regulating molecule 1, ADRM 1, Adrm1, ADRM1_HUMAN, ARM 1, ARM-1, ARM1, GP110, hRpn13, Mr 110,000 surface antigen, Proteasomal ubiquitin receptor ADRM1, proteasome regulatory particle non ATPase 13, Proteasome regulatory particle non-ATPase 13, Regulatory particle non ATPase 13, Rpn13, Rpn13 homolog.

Background: ADRM1 is a 407 amino acid protein that localizes to both the nucleus and the cytoplasm and is thought to be involved in protein recruitment and cell adhesion. An integral membrane protein, ADRM1 functions to recruit UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, and once at the proteasome it promotes the activity of UCH-L5. Additionally, ADRM1 is thought to mediate lymphocyte adhesion in endothelial cells and may thus play a role in lymphocyte homing. ADRM1 expression is induced by IFN-g in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis. Two isoforms of ADRM1 exist due to alternative splicing events.

ID gène: 11047

Pathways: Positive Regulation of Endopeptidase Activity