Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

APC2 anticorps (AA 1-100)

APC2 Reactivité: Humain ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1714590
  • Antigène Voir toutes APC2 Anticorps
    APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
    Épitope
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivité
    • 28
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 27
    • 1
    Lapin
    Clonalité
    • 27
    • 1
    Polyclonal
    Conjugué
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp APC2 est non-conjugé
    Application
    • 12
    • 12
    • 10
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human APCL/APC2
    Isotype
    IgG
    Top Product
    Discover our top product APC2 Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
    Autre désignation
    APCL/APC2 (APC2 Produits)
    Synonymes
    anticorps APCL, anticorps AI852447, anticorps R75424, anticorps APC2, WNT signaling pathway regulator, anticorps adenomatosis polyposis coli 2, anticorps APC2, anticorps Apc2
    Sujet

    Synonyms: Adenomatous polyposis coli protein 2, Adenomatous polyposis coli protein-like, APCL, APC2_HUMAN.

    Background: The adenomatous polyposis syndromes, familial adenomatous polyposis (FAP) and Gardner?s syndrome (GS), are characterized by numerous adenomatous polyps throughout the entire colon. These polyps invariably progress to colon cancer in addition to other extracolonic manifestations. The cloning of the APC gene revealed a ubiquitously expressed protein, 2843 amino acids in length, which is frequently mutated in patients suffering from FAP and GS. APC has been found to be associated with structural components of intracellular junctions. b-catenin and g-catenin (also called plakoglobin) are involved in the regulation of cellular adhesion. APC and E cadherin compete for binding to specific internal regions of both b- and g-catenin. Interactions between cytoskeleton and the APC, E cadherin, b/g catenin complex are mediated by a-catenin.

    ID gène
    10297
    Pathways
    Signalisation WNT
Vous êtes ici:
Support technique