Caspase 6 anticorps (AA 181-293)

N° du produit ABIN1714708

Cet anticorps Lapin Polyclonal détecte spécifiquement Caspase 6 dans WB, IF (cc), IF (p), IHC (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Caspase 6 anticorps (AA 181-293) (ABIN1714708)

Antigène: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 6 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Caspase 6 anticorps

Épitope: AA 181-293

Fonction: Caspase-6 subunit p11 Antibody

Réactivité croisée: Humain, Souris, Rat, Poisson zèbre (Danio rerio)

Homologie: Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Caspase-6 subunit p11

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000),

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Caspase 6

Antigène: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Autre désignation: Caspase-6

Sujet:

Synonyms: Caspase-6 subunit p11, Caspase-6 p11, Apoptosis Related Cysteine Protease, Apoptotic cysteine protease MCH2, Apoptotic protease MCH 2, Apoptotic protease MCH2, Casp 6, Casp6, Caspase 6 apoptosis related cysteine protease, Caspase 6 precursor, Caspase6, Human cysteine protease Mch2 isoform alpha, Mch 2, Mch2, CASP6_HUMAN.

Background: Caspase-6 Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. Subunit is compose of heterodimer of a18 kDa (p18) and a 11 kDa (p11) subunit. Subcellular location at cytoplasmic. Cleavages by CPP32, caspase-8 or -10 generate the two active subunits. It belongs to the peptidase C14 family.

ID gène: 839

UniProt: P55212

Pathways: Apoptose, Caspase Cascade in Apoptosis