RRM2 anticorps (AA 151-250)
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- Antigène Voir toutes RRM2 Anticorps
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
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Épitope
- AA 151-250
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RRM2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human RRM2
- Isotype
- IgG
- Top Product
- Discover our top product RRM2 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
- Autre désignation
- RRM2 (RRM2 Produits)
- Synonymes
- anticorps R2, anticorps RR2, anticorps RR2M, anticorps AA407299, anticorps rrm2, anticorps rr2m, anticorps cb111, anticorps chunp6884, anticorps r2, anticorps ribonucleotide reductase regulatory subunit M2, anticorps ribonucleotide reductase M2, anticorps ribonucleotide reductase M2, gene 2 L homeolog, anticorps ribonucleotide reductase M2, gene 1, anticorps ribonucleotide reductase M2 polypeptide, anticorps RRM2, anticorps Rrm2, anticorps rrm2.2.L, anticorps rrm2.1, anticorps rrm2
- Sujet
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Synonyms: R2, Ribonucleoside-diphosphate reductase subunit M2, Ribonucleotide reductase M2 subunit, Ribonucleotide reductase small chain, Ribonucleotide reductase small subunit, RIR2_HUMAN, RR2, RR2M, RRM2.
Background: Ribonucleotide reductase is essential for the production and maintenance of the level of deoxyribonucleoside triphosphates (dNTPs) required for DNA synthesis. It is an enzymatic complex consisting of two nonidentical subunits, R1 and R2, which are inactive separately. R2, the smaller subunit, is localized to the cytoplasm. R2 is the limiting factor of the catalytic activity of the ribonucleotide reductase enzymatic complex. R2 expression is strictly correlated to the S-phase of the cell cycle, whereas R1 remains constant throughout all phases of the cell cycle. While R2 seems to be involved solely in the maintenance of dNTPs for DNA replication, a similar protein, p53R2, has been shown to be responsible for the production of dNTPs in response to DNA damage.
- ID gène
- 6241
- Pathways
- Mitotic G1-G1/S Phases
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