IFNA1 anticorps (AA 150-189)

N° du produit ABIN1715112

Cet anticorps anti-IFNA1 est un anticorps Lapin Polyclonal détectant IFNA1 dans WB, IHC (p) et IF (p). Adapté pour Souris.

Aperçu rapide pour IFNA1 anticorps (AA 150-189) (ABIN1715112)

Antigène: IFNA1 (Interferon, alpha 1 (IFNA1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFNA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-IFNA1 anticorps

Épitope: AA 150-189

Specificité: The antibody targets Mouse IFNA1 protein, but will cross-react with IFNA11 and IFNA16

Réactivité croisée: Souris

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse IFNA1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur IFNA1

Antigène: IFNA1 (Interferon, alpha 1 (IFNA1))

Autre désignation: IFNA1

Sujet:

Synonyms: IFN alpha, IFN-alpha-1, IFA1, Interferon alpha 1, IFNA1_MOUSE, IFNA11, IFNAB_MOUSE, IFN-alpha-11, Interferon alpha-11, Limitin, Q810G1_MOUSE, IFNA16, IFNA6T

Background: IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs can activate immune cells, such as natural killer cells and macrophages, they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes, and they also increase the ability of uninfected host cells to resist new infection by virus. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes. IFNA1 is produced by macrophages and has antiviral activities.

ID gène: 15962

UniProt: P01572

Pathways: Signalistation JAK/STAT, Hepatitis C