Hsc70 anticorps

N° du produit ABIN1721551

Cet anticorps Souris Monoclonal détecte spécifiquement Hsc70 dans WB, IHC, ELISA et IP. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour Hsc70 anticorps (ABIN1721551)

Antigène: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Hsc70 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Clone: 1F2-H5

Détail du produit anti-Hsc70 anticorps

Specificité: Reacts with human Hsc70 (Hsp73). Cross-reacts with mouse and rat protein.

Purification: Purified (protein G)

Immunogène: Human Hsc70

Isotype: IgG2a

Information d'application

Indications d'application: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB1 μg/mL ELISA1-10 μg/mL IHC1-10 μg/mL IP1-10 μg/mL

Positive control: HeLa cells

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.4

Conseil sur la manipulation: Dilute in PBS or medium which is identical to that used in the assay system.

Stock: 4 °C/-20 °C

Stockage commentaire: Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.

Date de péremption: 6 months

Détails sur Hsc70

Antigène: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Autre désignation: Hsc70 (Hsp73)

Sujet: Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.

Heat shock cognate 71 kDa protein Heat shock 70 kDa protein 8 Lipopolysaccharide-associated protein 1, LAP-1, LPS-associated protein 1 Gene name: HSPA8, HSC70, HSP73, HSPA10

ID gène: 3312

UniProt: P11142