IL1A anticorps

N° du produit ABIN1724632

Cet anticorps Souris Monoclonal détecte spécifiquement IL1A dans ELISA. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour IL1A anticorps (ABIN1724632)

Antigène: IL1A (Interleukin 1 alpha (IL1A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL1A est non-conjugé

Application: ELISA

Clone: 3A6F11

Détail du produit anti-IL1A anticorps

Fonction: IL-1a Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human IL1a expressed in E. Coli.

Isotype: IgG2a

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-IL1A (ABIN1724632)

Grimaldi, Casadei, Ferri, Veglia, Licastro, Annoni, Biunno, De Bellis, Sorbi, Mariani, Canal, Griffin, Franceschi: "Association of early-onset Alzheimer's disease with an interleukin-1alpha gene polymorphism." dans: Annals of neurology, Vol. 47, Issue 3, pp. 361-5, (2000) (PubMed).

Du, Dodel, Eastwood, Bales, Gao, Lohmüller, Müller, Kurz, Zimmer, Evans, Hake, Gasser, Oertel, Griffin, Paul, Farlow: "Association of an interleukin 1 alpha polymorphism with Alzheimer's disease." dans: Neurology, Vol. 55, Issue 4, pp. 480-3, (2000) (PubMed).

Détails sur IL1A

Antigène: IL1A (Interleukin 1 alpha (IL1A))

Autre désignation: IL-1a

Sujet: Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease

Poids moléculaire: 30.6 kDa

ID gène: 3552

UniProt: P01583

Pathways: Signalisation NF-kappaB, Autophagy, Cancer Immune Checkpoints