APOA5 anticorps

N° du produit ABIN1724647

Détail du produit anti-APOA5 anticorps

Antigène: APOA5 (Apolipoprotein A-V (APOA5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp APOA5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: purified

Immunogène: Purified recombinant fragment of human Apoa5 expressed in E. coli.

Clone: 2G1H11

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-APOA5 (ABIN1724647)

Prieur, Coste, Rodriguez: "The human apolipoprotein AV gene is regulated by peroxisome proliferator-activated receptor-alpha and contains a novel farnesoid X-activated receptor response element." dans: The Journal of biological chemistry, Vol. 278, Issue 28, pp. 25468-80, (2003) (PubMed).

Pennacchio, Olivier, Hubacek, Cohen, Cox, Fruchart, Krauss, Rubin: "An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing." dans: Science (New York, N.Y.), Vol. 294, Issue 5540, pp. 169-73, (2001) (PubMed).

Détails sur APOA5

Antigène: APOA5 (Apolipoprotein A-V (APOA5))

Autre désignation: APOA5 (APOA5 Produits)

Synonymes: anticorps APOAV, anticorps RAP3, anticorps 1300007O05Rik, anticorps Apoav, anticorps apo-AV, anticorps apoA-V, anticorps APOA5, anticorps MGC140487, anticorps rap3, anticorps apoav, anticorps apoa-v, anticorps apolipoprotein A5, anticorps apolipoprotein A-V, anticorps apolipoprotein A5 L homeolog, anticorps APOA5, anticorps Apoa5, anticorps apoa5.L, anticorps apoa5

Sujet:

Description: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70 % lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Despite these compelling molecular biology data, relatively little is known about ApoA5 protein in human serum. This antibody pair detected recombinant apoa5 protein in sandwich ELISA format and could be potential reagents for the development of clinical diagnostic kits.

Aliases: RAP3, APOAV, APOA-V, MGC126836, MGC126838

ID gène: 116519

HGNC: 116519

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism