CD31 anticorps

N° du produit ABIN1724665

Cet anticorps Souris Monoclonal détecte spécifiquement CD31 dans IHC, ELISA et ICC. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour CD31 anticorps (ABIN1724665)

Antigène: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD31 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Clone: 2F7B2

Détail du produit anti-CD31 anticorps

Fonction: CD31 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CD31 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-CD31 (ABIN1724665)

Wynne, Ball, McLellan, Dockery, Zimmermann, Moore: "Mouse pregnancy-specific glycoproteins: tissue-specific expression and evidence of association with maternal vasculature." dans: Reproduction (Cambridge, England), Vol. 131, Issue 4, pp. 721-32, (2006) (PubMed).

Bingle, Lewis, Corke, Reed, Brown: "Macrophages promote angiogenesis in human breast tumour spheroids in vivo." dans: British journal of cancer, Vol. 94, Issue 1, pp. 101-7, (2006) (PubMed).

Mayr, Zou, Zhang, Dietrich, Hu, Xu: "Accelerated arteriosclerosis of vein grafts in inducible NO synthase(-/-) mice is related to decreased endothelial progenitor cell repair." dans: Circulation research, Vol. 98, Issue 3, pp. 412-20, (2006) (PubMed).

Détails sur CD31

Antigène: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Autre désignation: CD31

Sujet: CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors.It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. The antibody reacts with the murine form of the Platelet-Endothelial Cell Adhesion Molecule. The reactivity of the antibody is restricted to the isoform of the molecule that is selectively expressed by endothelial cells.The antigen is predominantly present at the lateral borders of endothelial cells as described for human PECAM-1.It is also weakly expressed on many peripheral lymphoid cells and platelets.CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).

ID gène: 5175

UniProt: P16284

Pathways: Regulation of Actin Filament Polymerization