MYST1 anticorps

N° du produit ABIN1724671

Cet anticorps Souris Monoclonal détecte spécifiquement MYST1 dans WB, ELISA, IHC et ICC. Il présente une réactivité envers Humain et a été mentionné dans 4+ publications.

Aperçu rapide pour MYST1 anticorps (ABIN1724671)

Antigène: MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MYST1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: 8C4C4

Détail du produit anti-MYST1 anticorps

Fonction: MYST1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human MYST1 expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-MYST1 (ABIN1724671)

Jiang, Gao, Zheng, Yin, Wang, Zhong, Ali, Khan, Hao, Fang, Sun, Xu, Pandita, Jiang, Shi: "MOF influences meiotic expansion of H2AX phosphorylation and spermatogenesis in mice." dans: PLoS genetics, Vol. 14, Issue 5, pp. e1007300, (2018) (PubMed).

Akhtar, Becker: "The histone H4 acetyltransferase MOF uses a C2HC zinc finger for substrate recognition." dans: EMBO reports, Vol. 2, Issue 2, pp. 113-8, (2001) (PubMed).

Neal, Pannuti, Smith, Lucchesi: "A new human member of the MYST family of histone acetyl transferases with high sequence similarity to Drosophila MOF." dans: Biochimica et biophysica acta, Vol. 1490, Issue 1-2, pp. 170-4, (2000) (PubMed).

Sterner, Berger: "Acetylation of histones and transcription-related factors." dans: Microbiology and molecular biology reviews : MMBR, Vol. 64, Issue 2, pp. 435-59, (2000) (PubMed).

Détails sur MYST1

Antigène: MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))

Autre désignation: MYST1

Sujet: MYST1 (MYST histone acetyltransferase 1, MOF) belongs to the MYST family of histone acetyltransferases, which are employed in the cell to bring about transcriptional regulation. The MYST family includes MYST1, is named for the founding members MOZ, yeast YBF2 and SAS2, and TIP60. All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein- protein interactions and targeting transcriptional regulators to chromatin. Although MOF is expressed in both males and females, it associates with the X chromosome only in males. MOF contains a zinc-finger domain that is used to contact the globular part of the nucleosome and histone H4. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone

Poids moléculaire: 53 kDa

ID gène: 84148

UniProt: Q9H7Z6