MSH6 anticorps
(2 références)Aperçu rapide pour MSH6 anticorps (ABIN1724694)
Antigène
Voir toutes MSH6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- MSH6 Antibody
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Purification
- Ascitic fluid
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Immunogène
- Purified recombinant fragment of MSH6 expressed in E. Coli.
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Isotype
- IgG1
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anti-MutS Homolog 6 (E. Coli) (MSH6) antibody
MSH6 Reactivité: Humain WB, IHC, ELISA, FACS, ICC Hôte: Souris Monoclonal 3E1 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 Reactivité: Humain WB, IHC, ELISA, FACS, ICC Hôte: Souris Monoclonal 7D9H5 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 Reactivité: Humain WB, IHC, ELISA, FACS Hôte: Souris Monoclonal 2E3A10 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 217-395) antibodyMSH6 Reactivité: Humain, Souris, Singe WB, ELISA, FACS Hôte: Souris Monoclonal 1D1C2 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 931-1030) antibodyMSH6 Reactivité: Humain WB, ELISA, IF, PLA Hôte: Souris Monoclonal 1F2 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 Reactivité: Humain WB, IHC, ELISA, IF, Coat, StM Hôte: Souris Monoclonal MSH6-3091 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (N-Term) antibodyMSH6 Reactivité: Humain, Souris, Rat, Chien, Cobaye, Boeuf (Vache), Cheval, Lapin WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (Internal Region) antibodyMSH6 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 225-333) antibodyMSH6 Reactivité: Humain, Souris, Rat, Chien WB, IF Hôte: Souris Monoclonal 44-MSH6 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 1-400) antibodyMSH6 Reactivité: Humain IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- ELISA: 1/10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 3, pp. 558-63, (2006) (PubMed).
: "What the physician needs to know about Lynch syndrome: an update." dans: Oncology (Williston Park, N.Y.), Vol. 19, Issue 4, pp. 455-63; discussion 463-4, 466, 469, (2005) (PubMed).
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: "Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 3, pp. 558-63, (2006) (PubMed).
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- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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Autre désignation
- MSH6
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Sujet
- Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.
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ID gène
- 2956
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UniProt
- P52701
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Pathways
- Réparation de l'ADN, Chromatin Binding, Production of Molecular Mediator of Immune Response
Antigène
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