TYRO3 anticorps (AA 138-321)

N° du produit ABIN1724702

L’anticorps Souris Monoclonal anti-TYRO3 a été validé pour ELISA et ICC. Il convient pour détecter TYRO3 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour TYRO3 anticorps (AA 138-321) (ABIN1724702)

Antigène: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TYRO3 est non-conjugé

Application: ELISA, Immunocytochemistry (ICC)

Clone: 6D6F10

Détail du produit anti-TYRO3 anticorps

Épitope: AA 138-321

Fonction: Tyro3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of Tyro3 (aa138-321) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-TYRO3 (ABIN1724702)

Hafizi, Gustafsson, Stenhoff, Dahlbäck: "The Ran binding protein RanBPM interacts with Axl and Sky receptor tyrosine kinases." dans: The international journal of biochemistry & cell biology, Vol. 37, Issue 11, pp. 2344-56, (2005) (PubMed).

Détails sur TYRO3

Antigène: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Autre désignation: Tyro3

Sujet: Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98 kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.

UniProt: Q06418

Pathways: Signalisation RTK