Androgen Receptor anticorps

N° du produit ABIN1724724

Cet anticorps anti-Androgen Receptor est un anticorps Souris Monoclonal détectant Androgen Receptor dans WB, IHC et ELISA. Adapté pour Humain. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour Androgen Receptor anticorps (ABIN1724724)

Antigène: Androgen Receptor (AR)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Androgen Receptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 2H8

Détail du produit anti-Androgen Receptor anticorps

Fonction: Androgen receptor Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human AR expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Androgen Receptor (ABIN1724724)

Yu, Han, Shao, Wu, Zhao, Liu, Sun, Tang, Xia: "Androgen receptor functioned as a suppressor in the prostate cancer cell line PC3 in vitro and in vivo." dans: Chinese medical journal, Vol. 122, Issue 22, pp. 2779-83, (2009) (PubMed).

Hsu, Lan, Tsai, Ou, Cheng, Tsai, Kang, Tung, Wong, Huang: "Expression of androgen receptor in human placentas from normal and preeclamptic pregnancies." dans: Taiwanese journal of obstetrics & gynecology, Vol. 48, Issue 3, pp. 262-7, (2009) (PubMed).

Tillman, Yuan, Gu, Fazli, Ghosh, Flynt, Gleave, Rennie, Kasper: "DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells." dans: Cancer research, Vol. 67, Issue 10, pp. 4630-7, (2007) (PubMed).

Détails sur Androgen Receptor

Antigène: Androgen Receptor (AR)

Autre désignation: Androgen receptor

Sujet: The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression, however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.

Poids moléculaire: 110 kDa

ID gène: 367

UniProt: P10275

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding