DKK3 anticorps

N° du produit ABIN1724727

Cet anticorps anti-DKK3 est un anticorps Souris Monoclonal détectant DKK3 dans WB, ELISA et FACS. Adapté pour Humain et Singe. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour DKK3 anticorps (ABIN1724727)

Antigène: DKK3

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DKK3 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 4G7

Détail du produit anti-DKK3 anticorps

Fonction: DKK3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human DKK3 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-DKK3 (ABIN1724727)

Pei, Kano, Iijima, Morishita, Inadome, Noguchi: "Overexpression of Dickkopf 3 in hepatoblastomas and hepatocellular carcinomas." dans: Virchows Archiv : an international journal of pathology, Vol. 454, Issue 6, pp. 639-46, (2009) (PubMed).

Kurose, Sakaguchi, Nasu, Ebara, Kaku, Kariyama, Arao, Miyazaki, Tsushima, Namba, Kumon, Huh: "Decreased expression of REIC/Dkk-3 in human renal clear cell carcinoma." dans: The Journal of urology, Vol. 171, Issue 3, pp. 1314-8, (2004) (PubMed).

Persson, Rosenquist, Sommarin: "Identification of a novel calreticulin isoform (Crt2) in human and mouse." dans: Gene, Vol. 297, Issue 1-2, pp. 151-8, (2002) (PubMed).

Détails sur DKK3

Antigène: DKK3

Sujet: Dkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.

Poids moléculaire: 38 kDa

ID gène: 27122

UniProt: Q9UBP4