PRDM1 anticorps

N° du produit ABIN1724737

Cet anticorps Souris Monoclonal détecte spécifiquement PRDM1 dans WB et ELISA. Il présente une réactivité envers Humain et Souris et a été mentionné dans 3+ publications.

Aperçu rapide pour PRDM1 anticorps (ABIN1724737)

Antigène: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PRDM1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 5E7

Détail du produit anti-PRDM1 anticorps

Fonction: PRDM1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human PRDM1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-PRDM1 (ABIN1724737)

Jiang, Gao, Sze, Xiong, Hou: "Transcription factors Xbp-1, Blimp-1, and BSAP are involved in the regulation of plasmacytic differentiation induced by 2-methoxyestradiol in myeloma cell lines." dans: International journal of hematology, Vol. 86, Issue 5, pp. 429-37, (2008) (PubMed).

Barrett, Hansoul, Nicolae, Cho, Duerr, Rioux, Brant, Silverberg, Taylor, Barmada, Bitton, Dassopoulos, Datta, Green, Griffiths, Kistner, Murtha, Regueiro, Rotter, Schumm, Steinhart, Targan, Xavier et al.: "Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. ..." dans: Nature genetics, Vol. 40, Issue 8, pp. 955-62, (2008) (PubMed).

Ancelin, Lange, Hajkova, Schneider, Bannister, Kouzarides, Surani: "Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells." dans: Nature cell biology, Vol. 8, Issue 6, pp. 623-30, (2006) (PubMed).

Détails sur PRDM1

Antigène: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Autre désignation: PRDM1

Sujet: PRDM1/Blimp1 is a repressor of beta-interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. The transcription of this gene is increased upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.

Poids moléculaire: 88 kDa

ID gène: 639

UniProt: O75626

Pathways: Regulation of Muscle Cell Differentiation