Osteoactivin anticorps (AA 31-260)

N° du produit ABIN1724859

Cet anticorps anti-Osteoactivin est un anticorps Souris Monoclonal détectant Osteoactivin dans WB, ELISA et IHC. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour Osteoactivin anticorps (AA 31-260) (ABIN1724859)

Antigène: Osteoactivin (GPNMB)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Osteoactivin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 7C10E5

Détail du produit anti-Osteoactivin anticorps

Épitope: AA 31-260

Fonction: GPNMB Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human GPNMB (AA: 31-260) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Osteoactivin (ABIN1724859)

Tsui, Chang, Feng, Chang, Juang: "Glycoprotein transmembrane nmb: an androgen-downregulated gene attenuates cell invasion and tumorigenesis in prostate carcinoma cells." dans: The Prostate, Vol. 72, Issue 13, pp. 1431-42, (2012) (PubMed).

Williams, Esmaeli, Soheili, Simantov, Gombos, Bedikian, Hwu: "GPNMB expression in uveal melanoma: a potential for targeted therapy." dans: Melanoma research, Vol. 20, Issue 3, pp. 184-90, (2010) (PubMed).

Détails sur Osteoactivin

Antigène: Osteoactivin (GPNMB)

Autre désignation: GPNMB

Sujet: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 64 kDa

UniProt: Q14956