Osteoactivin anticorps (N-Term)

N° du produit ABIN2781893

Cet anticorps anti-Osteoactivin Polyclonal Lapin (ABIN2781893) détecte spécifiquement Osteoactivin dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Cobaye et Lapin.

Aperçu rapide pour Osteoactivin anticorps (N-Term) (ABIN2781893)

Antigène: Osteoactivin (GPNMB)

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Osteoactivin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Osteoactivin anticorps

Épitope: N-Term

Fonction: GPNMB Antibody - N-terminal region

Séquence: DENDWNEKLY PVWKRGDMRW KNSWKGGRVQ AVLTSDSPAL VGSNITFAVN

Specificité: 100 % homologous to both isoforms of hGPNMB

Homologie: Cow: 100%, Dog: 79%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against GPNMB. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GPNMB

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44499-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Osteoactivin

Antigène: Osteoactivin (GPNMB)

Autre désignation: GPNMB

Sujet:

Background Information: GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential.The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Glycoprotein (transmembrane) nmb

Alternative Symbols: NMB, HGFIN, PLCA3

Protein Name: cDNA FLJ78601, highly similar to Homo sapiens glycoprotein (transmembrane) nmb (GPNMB), transcript variant 2, mRNA EMBL BAF84767.1

Poids moléculaire: 63 kDa

ID gène: 10457

NCBI Accession: NP_002501

UniProt: Q14956