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CD25 anticorps (AA 34-139)

IL2RA Reactivité: Humain, Souris, Rat, Singe WB, IHC, ELISA, ICC Hôte: Souris Monoclonal 1B5D12 unconjugated
N° du produit ABIN1724861
  • Antigène Voir toutes CD25 (IL2RA) Anticorps
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Épitope
    • 16
    • 10
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 34-139
    Reactivité
    • 186
    • 126
    • 37
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Singe
    Hôte
    • 148
    • 98
    • 80
    • 2
    • 1
    Souris
    Clonalité
    • 248
    • 77
    • 2
    Monoclonal
    Conjugué
    • 112
    • 34
    • 29
    • 27
    • 22
    • 11
    • 8
    • 8
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD25 est non-conjugé
    Application
    • 223
    • 90
    • 56
    • 49
    • 43
    • 41
    • 22
    • 18
    • 14
    • 13
    • 10
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human IL2RA (AA: 34-139) expressed in E. coli.
    Clone
    1B5D12
    Isotype
    IgG1
    Top Product
    Discover our top product IL2RA Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Shvidel, Braester, Bairey, Rahimi-Levene, Herishanu, Tadmor, Klepfish, Ruchlemer, Shtalrid, Berrebi, Polliack: "Cell surface expression of CD25 antigen (surface IL-2 receptor α-chain) is not a prognostic marker in chronic lymphocytic leukemia: results of a retrospective study of 281 patients." dans: Annals of hematology, Vol. 91, Issue 10, pp. 1597-602, (2012) (PubMed).

    Sun, Wang, Zhu, Fang, Yu, Xu: "The interleukin-2 receptor α chain (CD25) plays an important role in regulating monocyte-derived CD40 expression during anti-porcine cellular responses." dans: Transplantation proceedings, Vol. 44, Issue 4, pp. 1139-42, (2012) (PubMed).

  • Antigène
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Autre désignation
    IL2RA (IL2RA Produits)
    Synonymes
    anticorps CD25, anticorps IDDM10, anticorps IL2R, anticorps TCGFR, anticorps IL2RAC, anticorps IL-2RA, anticorps Il2r, anticorps Ly-43, anticorps interleukin 2 receptor subunit alpha, anticorps interleukin-2 receptor subunit alpha-like, anticorps interleukin 2 receptor, alpha chain, anticorps IL2RA, anticorps Il2ra, anticorps LOC100222957
    Sujet

    Description: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. , , , ,

    Aliases: CD25, IL2R, TCGFR, IDDM10

    Poids moléculaire
    30.8 kDa
    ID gène
    3559
    HGNC
    3559
    Pathways
    Signalistation JAK/STAT, Growth Factor Binding, Activated T Cell Proliferation
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