Decorin anticorps (AA 263-324)

N° du produit ABIN1724881

Cet anticorps Souris Monoclonal détecte spécifiquement Decorin dans ELISA et FACS. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour Decorin anticorps (AA 263-324) (ABIN1724881)

Antigène: Decorin (DCN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Decorin est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 5E8E7

Détail du produit anti-Decorin anticorps

Épitope: AA 263-324

Fonction: DCN Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human DCN (AA: 263-324) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Decorin (ABIN1724881)

Buraschi, Neill, Owens, Iniguez, Purkins, Vadigepalli, Evans, Schaefer, Peiper, Wang, Iozzo: "Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model." dans: PLoS ONE, Vol. 7, Issue 9, pp. e45559, (2012) (PubMed).

Adam, Saller, Ströbl, Hennebold, Dissen, Ojeda, Stouffer, Berg, Berg, Mayerhofer: "Decorin is a part of the ovarian extracellular matrix in primates and may act as a signaling molecule." dans: Human reproduction (Oxford, England), Vol. 27, Issue 11, pp. 3249-58, (2012) (PubMed).

Détails sur Decorin

Antigène: Decorin (DCN)

Autre désignation: DCN

Sujet: The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.

Poids moléculaire: 39.7 kDa

ID gène: 1634

UniProt: P07585

Pathways: Glycosaminoglycan Metabolic Process