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MCAM anticorps (AA 84-189)

Name: MCAM anticorps (AA 84-189)
Brand: antibodies-online
SKU: ABIN1724898
Price: 644.71 EUR
Availability: InStock

MCAM Reactivité: Humain IHC, WB, ELISA Hôte: Souris Monoclonal 6C3F1 unconjugated

Immunohistochemical analysis of paraffin-embedded liver cancer tissues using MCAM mouse mAb with DAB staining. (MCAM anticorps (AA 84-189))

IHC

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (MCAM anticorps (AA 84-189))

ELISA

Western blot analysis using MCAM mouse mAb against Hela cell lysate. (MCAM anticorps (AA 84-189))

Western blot analysis using MCAM mAb against human MCAM recombinant protein. (MCAM anticorps (AA 84-189))

Western blot analysis using MCAM mAb against HEK293 (1) and MCAM (AA: 84-189)-hIgGFc transfected HEK293 (2) cell lysate. (MCAM anticorps (AA 84-189))

Immunohistochemical analysis of paraffin-embedded kidney tissues using MCAM mouse mAb with DAB staining. (MCAM anticorps (AA 84-189))

IHC

6 images

(2 références)

N° du produit ABIN1724898

Fiche de données

Antigène Voir toutes MCAM Anticorps

MCAM (Melanoma Cell Adhesion Molecule (MCAM))
Épitope
16

13

11

6

4

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 84-189
Reactivité
137

54

48

15

14

9

9

8

6

2
Humain
Hôte
96

65

8

1

1

1
Souris
Anticorps secondaires appropriés
Clonalité
87

85
Monoclonal
Conjugué
77

15

14

11

7

5

4

4

4

3

3

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp MCAM est non-conjugé
Application
94

85

68

45

24

22

18

12

12

5

4

4

3

3

2

1

1

1

1
Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Purification

purified

Immunogène

Purified recombinant fragment of human MCAM (AA: 84-189) expressed in E. coli.

Clone

6C3F1

Isotype

IgG1

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Indications d'application

ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C/-20 °C

Stockage commentaire

4°C, -20°C for long term storage
Wang, Yan: "CD146, a multi-functional molecule beyond adhesion." dans: Cancer letters, Vol. 330, Issue 2, pp. 150-62, (2013) (PubMed).

Jouve, Despoix, Espeli, Gauthier, Cypowyj, Fallague, Schiff, Dignat-George, Vély, Leroyer: "The involvement of CD146 and its novel ligand Galectin-1 in apoptotic regulation of endothelial cells." dans: The Journal of biological chemistry, Vol. 288, Issue 4, pp. 2571-9, (2013) (PubMed).
Antigène

MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Autre désignation

MCAM (MCAM Produits)

Synonymes

anticorps CD146, anticorps MUC18, anticorps Muc18, anticorps 1-gicerin, anticorps AV025631, anticorps CD149, anticorps s-endo, anticorps s-gicerin, anticorps cd146, anticorps gicerin, anticorps id:ibd3512, anticorps mcam, anticorps MCAM, anticorps melanoma cell adhesion molecule, anticorps melanoma cell adhesion molecule b, anticorps MCAM, anticorps Mcam, anticorps mcamb

Sujet

Description: The protein encoded by this gene plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during , embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration ,
Aliases: CD146, MUC18

Poids moléculaire

71.6 kDa

ID gène

4162

HGNC

4162