DIS3L2 anticorps (AA 27-250)

N° du produit ABIN1724900

L’anticorps Souris Monoclonal anti-DIS3L2 a été validé pour WB, ELISA, IHC et FACS. Il convient pour détecter DIS3L2 dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour DIS3L2 anticorps (AA 27-250) (ABIN1724900)

Antigène: DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DIS3L2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 6C7B2

Détail du produit anti-DIS3L2 anticorps

Épitope: AA 27-250

Fonction: DIS3L2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human DIS3L2 (AA: 27-250) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-DIS3L2 (ABIN1724900)

Du Toit: "Cytoskeleton: Formins induce nuclear actin assembly." dans: Nature reviews. Molecular cell biology, Vol. 14, Issue 6, pp. 328, (2013) (PubMed).

Astuti, Morris, Cooper, Staals, Wake, Fews, Gill, Gentle, Shuib, Ricketts, Cole, van Essen, van Lingen, Neri, Opitz, Rump, Stolte-Dijkstra, Müller, Pruijn, Latif, Maher: "Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility." dans: Nature genetics, Vol. 44, Issue 3, pp. 277-84, (2012) (PubMed).

Détails sur DIS3L2

Antigène: DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

Autre désignation: DIS3L2

Sujet: The protein encoded by this gene is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene.

Poids moléculaire: 99.3 kDa

ID gène: 129563

UniProt: Q8IYB7

Pathways: Stem Cell Maintenance