DIS3L2 anticorps (AA 201-400) (HRP)

N° du produit ABIN7150020

Détail du produit anti-DIS3L2 anticorps (HRP)

Antigène: DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

Épitope: AA 201-400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DIS3L2 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human DIS3-like exonuclease 2 protein (201-400AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DIS3L2

Antigène: DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

Autre désignation: DIS3L2 (DIS3L2 Produits)

Synonymes: anticorps RGD1560168, anticorps DIS3L2, anticorps DKFZp469O0522, anticorps FAM6A, anticorps PRLMNS, anticorps hDIS3L2, anticorps 4930429A22Rik, anticorps 8030493P09Rik, anticorps DIS3-like 3'-5' exoribonuclease 2, anticorps DIS3 like 3'-5' exoribonuclease 2, anticorps DIS3-like exonuclease 2, anticorps Dis3l2, anticorps DIS3L2, anticorps LOC100344728

Sujet:

Background: 3\'-5\'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3\' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3\'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.

Aliases: DI3L2_HUMAN antibody, DIS3 L2 antibody, DIS3 mitotic control homolog (S. cerevisiae) like 2 antibody, DIS3 mitotic control homolog like 2 antibody, DIS3-like exonuclease 2 antibody, Dis3l2 antibody, FLJ36974 antibody, MGC42174 antibody

UniProt: Q8IYB7

Pathways: Stem Cell Maintenance