SOX10 anticorps (AA 147-252)

N° du produit ABIN1724912

L’anticorps Souris Monoclonal anti-SOX10 a été validé pour IHC et ELISA. Il convient pour détecter SOX10 dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour SOX10 anticorps (AA 147-252) (ABIN1724912)

Antigène: SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SOX10 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Clone: 2E7E8

Détail du produit anti-SOX10 anticorps

Épitope: AA 147-252

Fonction: SOX10 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human SOX10 (AA: 147-252) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-SOX10 (ABIN1724912)

Shin, Vincent, Cuda, Xu, Kang, Kim, Taube: "Sox10 is expressed in primary melanocytic neoplasms of various histologies but not in fibrohistiocytic proliferations and histiocytoses." dans: Journal of the American Academy of Dermatology, Vol. 67, Issue 4, pp. 717-26, (2012) (PubMed).

Bannykh, Stolt, Kim, Perry, Wegner: "Oligodendroglial-specific transcriptional factor SOX10 is ubiquitously expressed in human gliomas." dans: Journal of neuro-oncology, Vol. 76, Issue 2, pp. 115-27, (2006) (PubMed).

Détails sur SOX10

Antigène: SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

Autre désignation: SOX10

Sujet: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Poids moléculaire: 49.9 kDa

ID gène: 6663

UniProt: P56693

Pathways: Chromatin Binding