MLXIPL anticorps (AA 18-143)
Aperçu rapide pour MLXIPL anticorps (AA 18-143) (ABIN1724913)
Antigène
Voir toutes MLXIPL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 18-143
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Fonction
- MLXIPL Antibody
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Purification
- Ascitic fluid
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Immunogène
- Purified recombinant fragment of human MLXIPL (AA: 18-143) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cells." dans: Diabetes, Vol. 61, Issue 3, pp. 574-85, (2012) (PubMed).
: "ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity." dans: Biochimica et biophysica acta, Vol. 1811, Issue 12, pp. 1194-200, (2011) (PubMed).
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: "Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cells." dans: Diabetes, Vol. 61, Issue 3, pp. 574-85, (2012) (PubMed).
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- MLXIPL (MLX Interacting Protein-Like (MLXIPL))
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Autre désignation
- MLXIPL
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Sujet
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This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.
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Poids moléculaire
- 93.1 kDa
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UniProt
- Q9NP71
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Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
Antigène
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