CDX2 anticorps (AA 176-303)

N° du produit ABIN1724918

Il existe 2+ publications pour ce produit. L’anticorps anti-CDX2 Monoclonal Souris est utilisé pour la détection de CDX2 dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour CDX2 anticorps (AA 176-303) (ABIN1724918)

Antigène: CDX2 (Caudal Type Homeobox 2 (CDX2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDX2 est non-conjugé

Application: ELISA

Clone: 2F12A6

Détail du produit anti-CDX2 anticorps

Épitope: AA 176-303

Fonction: CDX2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CDX2 (AA: 176-303) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-CDX2 (ABIN1724918)

Lee, Vogt, Hsiao, Osunkoya: "CDX-2 expression in malignant germ cell tumors of the testes, intratubular germ cell neoplasia, and normal seminiferous tubules." dans: Tumour biology, Vol. 33, Issue 6, pp. 2185-8, (2012) (PubMed).

Liu, Zhang, Zhan, Brock, Herman, Guo: "CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer." dans: Cancer biology & therapy, Vol. 13, Issue 12, pp. 1152-7, (2012) (PubMed).

Détails sur CDX2

Antigène: CDX2 (Caudal Type Homeobox 2 (CDX2))

Autre désignation: CDX2

Sujet: This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.

Poids moléculaire: 33.5 kDa

UniProt: Q99626

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance