Syndecan 1 anticorps (AA 28-171)

N° du produit ABIN1724936

L’anticorps Souris Monoclonal anti-Syndecan 1 a été validé pour WB, FACS, IHC, ELISA et ICC. Il convient pour détecter Syndecan 1 dans des échantillons de Humain et Souris. Il y a 2+ publications disponibles.

Aperçu rapide pour Syndecan 1 anticorps (AA 28-171) (ABIN1724936)

Antigène: Syndecan 1 (SDC1)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Syndecan 1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Clone: 1A3H4

Détail du produit anti-Syndecan 1 anticorps

Épitope: AA 28-171

Fonction: SDC1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human SDC1 (AA: 28-171) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Syndecan 1 (ABIN1724936)

Nunez, Siegal, Reddy, Wei: "CD138 (syndecan-1) expression in bone-forming tumors." dans: American journal of clinical pathology, Vol. 137, Issue 3, pp. 423-8, (2012) (PubMed).

Karasneh, Ali, Shukla: "An important role for syndecan-1 in herpes simplex virus type-1 induced cell-to-cell fusion and virus spread." dans: PLoS ONE, Vol. 6, Issue 9, pp. e25252, (2011) (PubMed).

Détails sur Syndecan 1

Antigène: Syndecan 1 (SDC1)

Autre désignation: SDC1

Sujet: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Poids moléculaire: 32.5 kDa

ID gène: 6382

UniProt: P18827

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism