TRF2 anticorps (AA 324-500)

N° du produit ABIN1724941

Cet anticorps Souris Monoclonal détecte spécifiquement TRF2 dans ELISA et IHC. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour TRF2 anticorps (AA 324-500) (ABIN1724941)

Antigène: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TRF2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 3H6B4

Détail du produit anti-TRF2 anticorps

Épitope: AA 324-500

Fonction: TERF2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human TERF2 (AA: 324-500) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-TRF2 (ABIN1724941)

Galati, Magdinier, Colasanti, Bauwens, Pinte, Ricordy, Giraud-Panis, Pusch, Savino, Cacchione, Gilson: "TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner." dans: PLoS ONE, Vol. 7, Issue 4, pp. e34386, (2012) (PubMed).

Diehl, Idowu, Kimmelshue, York, Jackson-Cook, Turner, Holt, Elmore: "Elevated TRF2 in advanced breast cancers with short telomeres." dans: Breast cancer research and treatment, Vol. 127, Issue 3, pp. 623-30, (2011) (PubMed).

Détails sur TRF2

Antigène: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Autre désignation: TERF2

Sujet: This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.

Poids moléculaire: 55.6 kDa

UniProt: Q15554

Pathways: Cycle Cellulaire, Telomere Maintenance