Amyloid Fibrils anticorps

N° du produit ABIN1731752

Détail du produit

Antigène: Amyloid Fibrils

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Dot Blot (DB)

Specificité: Reacts withepitopes common to many human amyloid fibrils and fibrillar oligomers but not prefibrillar oligomers or natively folded proteins. Predicted to recognize mouse and rat based on sequence homology.

Purification: Purified

Immunogène: Fibrils prepared from human Abeta42 peptide

Isotype: IgG

Information d'application

Indications d'application: Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB1 -2 μg/mL DB0.5 - 1 μg/mL IHC1 -5 μg/mL ELISA1 - 10 μg/mL with amyloid fibril-containing samples on the solid phase.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS pH 7.0, 50 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Dilute in PBS or medium which is identical to that used in the assay system.

Stock: -20 °C

Stockage commentaire: This product is stable for at least 1 year at -20°C. Freeze in multiple aliquots to avoid repeated freeze-thaw cycles.

Détail du antigène

Antigène: Amyloid Fibrils

Sujet: Amyloid monomeric proteins can oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibers.