BIM anticorps (AA 22-40)

N° du produit ABIN1732339

Cet anticorps Lapin Polyclonal détecte spécifiquement BIM dans WB et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour BIM anticorps (AA 22-40) (ABIN1732339)

Antigène: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-BIM anticorps

Épitope: AA 22-40

Specificité: Reacts with the internal domain of human, mouse and rat Bim.

Purification: Purified

Immunogène: Peptide corresponding to aa 22-40 of human Bim. The sequence is identical to that of mouse and is different by one amino acid from that of rat.

Isotype: IgG

Information d'application

Indications d'application: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(1 μg/mL) IHC(10 - 20 μg/mL)

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.4,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Dilute in PBS or medium that is identical to that used in the assay system.

Stock: -20 °C

Stockage commentaire: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Date de péremption: 12 months

Détails sur BIM

Antigène: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Autre désignation: Bim

Sujet: Bim/BOD interacts with diverse members in the prosurvival Bcl-2 subfamily including Bcl-2, Bcl-xL, and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.

Bcl-2-like protein 11, Bcl2-L-11 Bcl2-interacting mediator of cell death Gene name: BCL2L11, BIM, BAM, BOD

ID gène: 10018

UniProt: O43521

Pathways: Signalisation PI3K-Akt, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity