BIM anticorps (AA 22-40)

N° du produit ABIN1732339

Cet anticorps Lapin Polyclonal détecte spécifiquement BIM dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BIM anticorps (AA 22-40) (ABIN1732339)

Antigène: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-BIM anticorps

Épitope: AA 22-40

Specificité: Reacts with the internal domain of human, mouse and rat Bim.

Purification: Purified

Immunogène: Peptide corresponding to aa 22-40 of human Bim. The sequence is identical to that of mouse and is different by one amino acid from that of rat.

Isotype: IgG

Information d'application

Indications d'application: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(1 μg/mL) IHC(10 - 20 μg/mL)

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.4,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Dilute in PBS or medium that is identical to that used in the assay system.

Stock: -20 °C

Stockage commentaire: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Date de péremption: 12 months

Détails sur BIM

Antigène: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Autre désignation: Bim

Sujet: Bim/BOD interacts with diverse members in the prosurvival Bcl-2 subfamily including Bcl-2, Bcl-xL, and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.

Bcl-2-like protein 11, Bcl2-L-11 Bcl2-interacting mediator of cell death Gene name: BCL2L11, BIM, BAM, BOD

ID gène: 10018

UniProt: O43521

Pathways: Signalisation PI3K-Akt, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity