F12 anticorps
Aperçu rapide pour F12 anticorps (ABIN1734212)
Antigène
Voir toutes F12 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Reacts with human F12 / Factor XII
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Réactivité croisée (Details)
- Specific for Factor XII as demonstrated by immunodiffusion. A single precipitin arc was obtained with normal plasma and no reaction was observed with F. XII-deficient plasma.
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Purification
- Purified
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Immunogène
- Activated human Factor XII (F XIIa) purified from plasma.
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Isotype
- IgG
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Indications d'application
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Working dilution: IHC-P (5 μg/mL)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 10 mM HEPES, pH 7.4, 0.15 M NaCl, 50 % glycerol.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Long term: -20°C, Short term: +4°C. Avoid repeat freeze-thaw cycles.
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- F12 (Coagulation Factor XII (F12))
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Autre désignation
- F12 / Factor XII
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Sujet
- Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
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Pathways
- Système du Complément
Antigène
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