PARK7/DJ1 anticorps (N-Term)

N° du produit ABIN1737863

L’anticorps Lapin Polyclonal anti-PARK7/DJ1 a été validé pour WB. Il convient pour détecter PARK7/DJ1 dans des échantillons de Humain et Souris.

Aperçu rapide pour PARK7/DJ1 anticorps (N-Term) (ABIN1737863)

Antigène: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARK7/DJ1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PARK7/DJ1 anticorps

Épitope: AA 167-189, N-Term

Specificité: Reacts with human and mouse PARK7. Sequence homology to mouse and rat DJ-1 is 82 % .

Purification: Purified

Immunogène: Synthetic peptide corresponding to amino acids 167-189 (AIVEALNGKEVAAQVKAPLVLKD) of human PARK7 conjugated to KLH at the N-terminus.

Isotype: IgG

Information d'application

Indications d'application: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB1:500

Positive control: HEK293 cell lysate or mouse brain tissue lysate

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.4,

Conseil sur la manipulation: Dilute in PBS or medium which is identical to that used in the assay system.

Stock: 4 °C/-20 °C

Stockage commentaire: Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.

Date de péremption: 6 months

Détails sur PARK7/DJ1

Antigène: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Autre désignation: Park7

Sujet: Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.

Protein DJ-1 Oncogene DJ1 Parkinson disease protein 7 Gene name: PARK7

ID gène: 11315

UniProt: Q99497

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport