PINK1 anticorps (Internal Region)
-
- Antigène Voir toutes PINK1 Anticorps
- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
-
Épitope
- AA 350-500, Internal Region
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp PINK1 est non-conjugé
-
Application
- Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- Reacts with human and mouse PINK1 protein
- Purification
- Antigen affinity purified
- Immunogène
- A genomic peptide made to an internal region of the human PINK1 protein (within residues 350-500).
- Isotype
- IgG
- Top Product
- Discover our top product PINK1 Anticorps primaire
-
-
- Indications d'application
-
Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC/IF1:500-1:1000, IHC1:100, IHC-P 1:100 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.17 mg/mL
- Buffer
- PBS, Sodium azide 0.05 %
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Date de péremption
- 6 months
-
- Antigène
- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
- Autre désignation
- PINK1 (PINK1 Produits)
- Synonymes
- anticorps BEST:GH23468, anticorps CG4523, anticorps Dmel\\CG4523, anticorps PINK, anticorps PINK1, anticorps dPINK1, anticorps dPink1, anticorps pink1, anticorps wu:fc39e12, anticorps zgc:101729, anticorps BRPK, anticorps PARK6, anticorps 1190006F07Rik, anticorps AU042772, anticorps AW557854, anticorps mFLJ00387, anticorps PTEN-induced putative kinase 1, anticorps PTEN induced putative kinase 1, anticorps Pink1, anticorps PINK1, anticorps pink1
- Sujet
- PTEN induced putative kinase 1 (Pink1) was first discovered when researching the PTEN signaling pathway, thus Pink1 is also involved in many human cancers.It is found in the mitochondria and its homozygous C-terminus mutation has been implicated in the early development of Parkinson's disease. It protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2.
- ID gène
- 65018
- UniProt
- Q9BXM7
- Pathways
- Autophagy
-