RAD17 anticorps (N-Term)

N° du produit ABIN1738687

Cet anticorps Lapin Polyclonal détecte spécifiquement RAD17 dans WB et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour RAD17 anticorps (N-Term) (ABIN1738687)

Antigène: RAD17

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD17 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-RAD17 anticorps

Épitope: N-Term

Specificité: Reacts with human Rad17

Purification: Purified

Immunogène: Synthetic peptide made to a N-terminal region of human RAD17.

Isotype: IgG

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/1 000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, Sodium azide 0.01 %

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 6 months

Détails sur RAD17

Antigène: RAD17

Autre désignation: Rad17

Sujet: Signals originating from damaged DNA activate checkpoint pathways and target the mitotic apparatus via a number a distinct mechanisms.These checkpoints link damage to DNA with the components of the cell cycle through signal transduction systems. In mammals, five genes have been identified as components of DNA damage-induced checkpoint pathways: ATM, p53, p21/WAF1/CIP1, hCHK1, and 14-3-3sigma.When overexpressed in mammalian cells, hRAD17 activates p53 and causes an accumulation of G1 phase cells, suggesting an involvement of the hRAD17 gene in this checkpoint pathway.