RAB27A anticorps (AA 1-221)

N° du produit ABIN1742354

L’anticorps Lapin Polyclonal anti-RAB27A a été validé pour WB, IP et IHC (p). Il convient pour détecter RAB27A dans des échantillons de Humain, Souris et Rat. Il y a 2+ publications disponibles.

Aperçu rapide pour RAB27A anticorps (AA 1-221) (ABIN1742354)

Antigène: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB27A est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: KO Validated

Détail du produit anti-RAB27A anticorps

Épitope: AA 1-221

Fonction: Rabbit anti-Rab27A antibody

Specificité: Specific for rab 27A

Réactivité croisée (Details): Reacts with: rat (P23640), mouse (Q9ERI2), human (P51159). Other species not tested yet.

Purification: affinity purified

Immunogène: Recombinant protein corresponding to AA 1 to 221 from rat Rab27A (UniProt Id: P23640)

Information d'application

Indications d'application: WB:1 : 1000 , IP:yes ICC:not tested yet IHC:not tested yet IHC-P:1 : 2000,

Commentaires:

Only the non-conserved C-terminal part of the protein was used for affinity purification to achieve specificity.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin was added for stabilization.

Conseil sur la manipulation: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Stock: -20 °C,-80 °C,4 °C

Stockage commentaire: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin was added for stabilization. Do not freeze!

Références pour anticorps anti-RAB27A (ABIN1742354)

Hou, Ernst, Stuenkel, Lentz, Williams: "Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion." dans: PLoS ONE, Vol. 10, Issue 5, pp. e0125596, (2015) (PubMed).

Lovis, Roggli, Laybutt, Gattesco, Yang, Widmann, Abderrahmani, Regazzi: "Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction." dans: Diabetes, Vol. 57, Issue 10, pp. 2728-36, (2008) (PubMed).

Détails sur RAB27A

Antigène: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Autre désignation: Rab27A

Sujet:

Synonyms: Rab27, pancreas, insulin granules, secretory vesicles, pancreatic islands

Antigen Information: K.O. Rab27 proteins are members of the Rab family responsible for melanosomal transport and hormone secretion

UniProt: P23640

Pathways: Peptide Hormone Metabolism