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TNC anticorps

L’anticorps Rat Monoclonal anti-TNC a été validé pour WB, IHC et ICC. Il convient pour détecter TNC dans des échantillons de Rat et Souris. Il y a 5+ publications disponibles.
N° du produit ABIN1742432

Aperçu rapide pour TNC anticorps (ABIN1742432)

Antigène

Voir toutes TNC Anticorps
TNC (Tenascin C (TNC))

Reactivité

  • 109
  • 43
  • 43
  • 15
  • 2
  • 2
  • 1
  • 1
Rat, Souris

Hôte

  • 88
  • 45
  • 2
  • 1
  • 1
Rat

Clonalité

  • 74
  • 63
Monoclonal

Conjugué

  • 54
  • 14
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Cet anticorp TNC est non-conjugé

Application

  • 77
  • 49
  • 27
  • 26
  • 26
  • 19
  • 16
  • 16
  • 11
  • 11
  • 11
  • 10
  • 10
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone

578
  • Specificité

    Specific for tenascin-C splice variants carrying the FNIII D domain.

    Immunogène

    Glycopeptidase F-treated tenascin from mouse brain. Epitope FNIII D domain

    Isotype

    IgG
  • Indications d'application

    WB: 1:500 up to 1:1000, ICC: 1:100 up to 1:500, IHC: 1:500, IHC-P: 1:500 up to 1:1000,

    Commentaires

    Tenascin-C variants detected by this antibody are downregulated during development and hardly detectable in adult animals

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    For reconstitution add 200µl H2O.

    Agent conservateur

    Azide and BSA free

    Conseil sur la manipulation

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    Stock

    -20 °C

    Stockage commentaire

    Reconstitute and aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized.
  • Siddiqui, Horvat-Bröcker, Faissner: "The glia-derived extracellular matrix glycoprotein tenascin-C promotes embryonic and postnatal retina axon outgrowth via the alternatively spliced fibronectin type III domain TNfnD." dans: Neuron glia biology, Vol. 4, Issue 4, pp. 271-83, (2010) (PubMed).

    Rigato, Garwood, Calco, Heck, Faivre-Sarrailh, Faissner: "Tenascin-C promotes neurite outgrowth of embryonic hippocampal neurons through the alternatively spliced fibronectin type III BD domains via activation of the cell adhesion molecule F3/contactin." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 15, pp. 6596-609, (2002) (PubMed).

    Bartsch, Bartsch, Dörries, Faissner, Weller, Ekblom, Schachner: "Expression of tenascin in the developing and adult cerebellar cortex." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 12, Issue 3, pp. 736-49, (1992) (PubMed).

    Stern, Norris, Bronner-Fraser, Carlson, Faissner, Keynes, Schachner: "J1/tenascin-related molecules are not responsible for the segmented pattern of neural crest cells or motor axons in the chick embryo." dans: Development (Cambridge, England), Vol. 107, Issue 2, pp. 309-19, (1990) (PubMed).

    Gatchalian, Schachner, Sanes: "Fibroblasts that proliferate near denervated synaptic sites in skeletal muscle synthesize the adhesive molecules tenascin(J1), N-CAM, fibronectin, and a heparan sulfate proteoglycan." dans: The Journal of cell biology, Vol. 108, Issue 5, pp. 1873-90, (1989) (PubMed).

  • Antigène

    TNC (Tenascin C (TNC))

    Autre désignation

    Tenascin-C

    Sujet

    Synonyms: TN-C, J1-200/220, Cytoactin

    Pathways

    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development
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