TNC anticorps
Aperçu rapide pour TNC anticorps (ABIN1742432)
Antigène
Voir toutes TNC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Specific for tenascin-C splice variants carrying the FNIII D domain.
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Immunogène
- Glycopeptidase F-treated tenascin from mouse brain. Epitope FNIII D domain
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Isotype
- IgG
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Indications d'application
- WB: 1:500 up to 1:1000, ICC: 1:100 up to 1:500, IHC: 1:500, IHC-P: 1:500 up to 1:1000,
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Commentaires
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Tenascin-C variants detected by this antibody are downregulated during development and hardly detectable in adult animals
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- For reconstitution add 200µl H2O.
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Agent conservateur
- Azide and BSA free
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Conseil sur la manipulation
- Do not freeze! Antibodies should be stored at +4°C when still lyophilized.
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Stock
- -20 °C
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Stockage commentaire
- Reconstitute and aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized.
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: "The glia-derived extracellular matrix glycoprotein tenascin-C promotes embryonic and postnatal retina axon outgrowth via the alternatively spliced fibronectin type III domain TNfnD." dans: Neuron glia biology, Vol. 4, Issue 4, pp. 271-83, (2010) (PubMed).
: "Tenascin-C promotes neurite outgrowth of embryonic hippocampal neurons through the alternatively spliced fibronectin type III BD domains via activation of the cell adhesion molecule F3/contactin." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 15, pp. 6596-609, (2002) (PubMed).
: "Expression of tenascin in the developing and adult cerebellar cortex." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 12, Issue 3, pp. 736-49, (1992) (PubMed).
: "J1/tenascin-related molecules are not responsible for the segmented pattern of neural crest cells or motor axons in the chick embryo." dans: Development (Cambridge, England), Vol. 107, Issue 2, pp. 309-19, (1990) (PubMed).
: "Fibroblasts that proliferate near denervated synaptic sites in skeletal muscle synthesize the adhesive molecules tenascin(J1), N-CAM, fibronectin, and a heparan sulfate proteoglycan." dans: The Journal of cell biology, Vol. 108, Issue 5, pp. 1873-90, (1989) (PubMed).
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: "The glia-derived extracellular matrix glycoprotein tenascin-C promotes embryonic and postnatal retina axon outgrowth via the alternatively spliced fibronectin type III domain TNfnD." dans: Neuron glia biology, Vol. 4, Issue 4, pp. 271-83, (2010) (PubMed).
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- TNC (Tenascin C (TNC))
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Autre désignation
- Tenascin-C
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Sujet
- Synonyms: TN-C, J1-200/220, Cytoactin
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Pathways
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development
Antigène
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