ZYX anticorps (AA 1-572)
Aperçu rapide pour ZYX anticorps (AA 1-572) (ABIN1742558)
Antigène
Voir toutes ZYX AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-572
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Fonction
- Mouse anti-Zyxin IgG
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Specificité
- Specific for zyxin.
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Réactivité croisée (Details)
- Reacts with: human (Q15942), rat, mouse (Q62523), hamster. Other species not tested yet.
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Purification
- purified IgG
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Immunogène
- Recombinant protein corresponding to AA 1 to 572 from human Zyxin (UniProt Id: Q15942) Epitop AA 352 to 357 from human Zyxin (UniProt Id: Q15942)
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Isotype
- IgG1
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Indications d'application
- WB:1 : 100 up to 1 : 2000 , IP:yes ICC:1 : 100, IHC:not tested yet IHC-P:1 : 200,
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.
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Buffer
- PBS. Albumin and azide were added for stabilization.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze! Antibodies should be stored at +4°C when still lyophilized.
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Stock
- -20 °C,-80 °C,4 °C
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Stockage commentaire
- Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!
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: "Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin." dans: Scientific reports, Vol. 6, pp. 23258, (2016) (PubMed).
: "Cell shape-dependent early responses of fibroblasts to cyclic strain." dans: Biochimica et biophysica acta, Vol. 1833, Issue 12, pp. 3415-25, (2013) (PubMed).
: "Cell-penetrating peptides with intracellular actin-remodeling activity in malignant fibroblasts." dans: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7712-21, (2010) (PubMed).
: "Domain analysis of alpha-actinin reveals new aspects of its association with F-actin during cytokinesis." dans: Experimental cell research, Vol. 316, Issue 12, pp. 1925-34, (2010) (PubMed).
: "Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis." dans: Molecular biology of the cell, Vol. 20, Issue 13, pp. 3115-24, (2009) (PubMed).
: "mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes." dans: American journal of physiology. Renal physiology, Vol. 296, Issue 2, pp. F418-26, (2009) (PubMed).
: "Targeted disruption of the mouse Lipoma Preferred Partner gene." dans: Biochemical and biophysical research communications, Vol. 379, Issue 2, pp. 368-73, (2009) (PubMed).
: "Retrograde fluxes of focal adhesion proteins in response to cell migration and mechanical signals." dans: Molecular biology of the cell, Vol. 18, Issue 11, pp. 4519-27, (2007) (PubMed).
: "TES is a novel focal adhesion protein with a role in cell spreading." dans: Journal of cell science, Vol. 116, Issue Pt 5, pp. 897-906, (2003) (PubMed).
: "The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions." dans: The Journal of cell biology, Vol. 161, Issue 1, pp. 33-9, (2003) (PubMed).
: "Zyxin is not colocalized with vasodilator-stimulated phosphoprotein (VASP) at lamellipodial tips and exhibits different dynamics to vinculin, paxillin, and VASP in focal adhesions." dans: Molecular biology of the cell, Vol. 12, Issue 10, pp. 3103-13, (2001) (PubMed).
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- ZYX (Zyxin (ZYX))
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Autre désignation
- Zyxin
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Sujet
- Zyxin is involved in the regulation of actin dynamics
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UniProt
- Q15942
Antigène
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