Profilin anticorps (AA 1-140)

N° du produit ABIN1742559

Cet anticorps anti-Profilin est un anticorps Souris Monoclonal détectant Profilin dans WB, IHC et IHC (p). Adapté pour Humain, Boeuf (Vache), Cobaye, Opossum et Lapin. Ce Primary Antibody a été cité dans 6+ publications.

Aperçu rapide pour Profilin anticorps (AA 1-140) (ABIN1742559)

Antigène: Profilin (PFN)

Reactivité: Humain, Boeuf (Vache), Cobaye, Opossum, Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Profilin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2H11

Détail du produit anti-Profilin anticorps

Épitope: AA 1-140

Fonction: Mouse anti-Bovine Profilin IgG

Specificité: Specific for profilin 1.

Réactivité croisée (Details): Reacts with: human (P07737), cow, rabbit, Guinea pig, opossum. No signal: mouse (P62962). Other species not tested yet.

Purification: purified IgG

Immunogène: Recombinant protein corresponding to AA 1 to 140 from bovine Profilin1 (UniProt Id: P02584)

Isotype: IgG1

Information d'application

Indications d'application: WB:1 : 500 up to 1 : 5000 IHC:yes IHC-P:1 : 1000,

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS.

Conseil sur la manipulation: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Stock: -20 °C,-80 °C,4 °C

Stockage commentaire: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Do not freeze!

Références pour anticorps anti-Profilin (ABIN1742559)

Lorente, Syriani, Morales: "Actin filaments at the leading edge of cancer cells are characterized by a high mobile fraction and turnover regulation by profilin I." dans: PLoS ONE, Vol. 9, Issue 1, pp. e85817, (2014) (PubMed).

Giesemann, Schwarz, Nawrotzki, Berhörster, Rothkegel, Schlüter, Schrader, Schindelin, Mendel, Kirsch, Jockusch: "Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 23, Issue 23, pp. 8330-9, (2003) (PubMed).

Giesemann, Rathke-Hartlieb, Rothkegel, Bartsch, Buchmeier, Jockusch, Jockusch: "A role for polyproline motifs in the spinal muscular atrophy protein SMN. Profilins bind to and colocalize with smn in nuclear gems." dans: The Journal of biological chemistry, Vol. 274, Issue 53, pp. 37908-14, (2000) (PubMed).

Janke, Schlüter, Jandrig, Theile, Kölble, Arnold, Grinstein, Schwartz, Estevéz-Schwarz, Schlag, Jockusch, Scherneck: "Suppression of tumorigenicity in breast cancer cells by the microfilament protein profilin 1." dans: The Journal of experimental medicine, Vol. 191, Issue 10, pp. 1675-86, (2000) (PubMed).

Schlüter, Schleicher, Jockusch: "Effects of single amino acid substitutions in the actin-binding site on the biological activity of bovine profilin I." dans: Journal of cell science, Vol. 111 ( Pt 22), pp. 3261-73, (1999) (PubMed).

Wiedemann, Giehl, Almo, Fedorov, Girvin, Steinberger, Rüdiger, Ortner, Sippl, Dolecek, Kraft, Jockusch, Valenta: "Molecular and structural analysis of a continuous birch profilin epitope defined by a monoclonal antibody." dans: The Journal of biological chemistry, Vol. 271, Issue 47, pp. 29915-21, (1997) (PubMed).

Détails sur Profilin

Antigène: Profilin (PFN)

Autre désignation: Profilin

Sujet:

Synonyms: profilin

Antigen Information: Profilins are regulators of the microfilament network

UniProt: P02584