IDO1 anticorps (AA 78-184)

N° du produit ABIN180889

Cet anticorps Souris Monoclonal détecte spécifiquement IDO1 dans WB et IHC (fro). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour IDO1 anticorps (AA 78-184) (ABIN180889)

Antigène: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IDO1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 10-01-14

Détail du produit anti-IDO1 anticorps

Épitope: AA 78-184

Specificité: This Monoclonal antibody 10.1 recognizes Indoleamine-pyrrole 2,3-dioxygenase (IDO), an enzyme responsible for the catabolism of Tryptophan to N-Formlkynurenine and Kynurenine. In Western Blotting, it recognizes a 45 kDa band in IFN-gamma treated Human cell lines. This antibody recognizes a slightly lower Molecular Weight band in Mouse IDO compared to its Human counterpart.

Attributs du produit: Synonyms: IDO1, IDO, INDO, Indoleamine 2, 3-dioxygenase 1, EC=1.13.11.52, 3-dioxygenase,Indoleamine-pyrrole 2

Purification: Purified

Immunogène: Peptide corresponding to amino acids 78-184 of human IDO fused to GST

Isotype: IgG3

Information d'application

Indications d'application: Western Blot. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur IDO1

Antigène: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Autre désignation: IDO1 / INDO

Sujet: With the exception of tryptophan oxidase in hepatocytes, IDO is the only enzyme that degrades the amino acid tryptophan to kynurenine. Chlamydial pathogens require tryptophan for growth. IDO can lower available tryptophan in target cells leading to conversion of the pathogen to persistant forms, with significance in the progression to chronic infection with its associated pathological effects.Synonyms: 3-dioxygenase, 3-dioxygenase 1, EC=1.13.11.52, IDO, IDO1, INDO, Indoleamine 2, Indoleamine-pyrrole 2

ID gène: 3620

UniProt: P14902

Pathways: Activated T Cell Proliferation