Podoplanin anticorps
Aperçu rapide pour Podoplanin anticorps (ABIN180933)
Antigène
Voir toutes Podoplanin (PDPN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody recognizes Human Podoplanin (gp36).
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Attributs du produit
- Synonyms: Glycoprotein 36, PA2.26 antigen, T1-alpha, Aggrus, PDPN, GP36, PSEC0003, PSEC0025
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Purification
- Affinity chromatography on Protein G
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Immunogène
- ORF Human podoplanin ectodomain expressed in E. coliPage 1 of 3.
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Isotype
- IgG1
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Indications d'application
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Immunohistochemistry on frozen sections: 0.75g/mL - 2g/mL. Immunohistochemistry on paraffin sections: This product requires antigen retrieval usingheat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 isrecommended for this purpose. Recommended Positive Control: Normal lung
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 0,09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- Podoplanin (PDPN)
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Autre désignation
- Podoplanin
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Sujet
- Podoplanin a 36 kDa type I cell membrane-associated glycoprotein, with a broad spectrum of distribution, being strongly expressed on the lymphatic endothelium found in lung, placenta and skeletal muscle and to a lesser extent in brain, kidney and liver. Podoplanin is absent on blood endothelium and therefore This antibody is readily able to distinguish between lymphatic vessels and blood vasculature. Although the specific function of this protein is undetermined, Podoplanin is reported to be a reliable indicator of tumour lymphangiogenesis.Synonyms: Aggrus, GP36, Glycoprotein 36, PA2.26 antigen, PDPN, PSEC0003, PSEC0025, T1-alpha
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ID gène
- 10630
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UniProt
- Q86YL7
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Pathways
- Dicarboxylic Acid Transport
Antigène
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