Thyroglobulin anticorps

N° du produit ABIN180965

L’anticorps anti-Thyroglobulin Monoclonal Souris est utilisé pour la détection de Thyroglobulin dans des échantillons de Humain. Il a été validé pour EIA et ELISA (Capture).

Aperçu rapide pour Thyroglobulin anticorps (ABIN180965)

Antigène: Thyroglobulin (TG)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Thyroglobulin est non-conjugé

Application: Enzyme Immunoassay (EIA), ELISA (Capture)

Clone: BGN-6E10

Détail du produit anti-Thyroglobulin anticorps

Specificité: Reacts with different epitope to clone BGN/6D7 (BM733) and can be used as the coated antibody in 2 site assay with this clone.

Attributs du produit: Synonyms: Thyreoglobulin, TGN

Purification: Affinity Chromatography on Protein G.

Immunogène: Purified Native Human Thyreoglobulin.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Thyroglobulin

Antigène: Thyroglobulin (TG)

Sujet: Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.Synonyms: TGN, Thyreoglobulin

ID gène: 7038

UniProt: P01266

Pathways: Thyroid Hormone Synthesis