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CD79a anticorps (AA 202-216)

Cet anticorps anti-CD79a est un anticorps Souris Monoclonal détectant CD79a dans FACS, WB, IHC (p) et IHC (fro). Adapté pour Humain, Souris, Rat, Boeuf (Vache), Porc, Singe, Poulet, Lapin, Cheval, Cobaye et Chien.
N° du produit ABIN181099

Aperçu rapide pour CD79a anticorps (AA 202-216) (ABIN181099)

Antigène

Voir toutes CD79a (CD79A) Anticorps
CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Reactivité

  • 221
  • 105
  • 83
  • 65
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  • 45
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Humain, Souris, Rat, Boeuf (Vache), Porc, Singe, Poulet, Lapin, Cheval, Cobaye, Chien

Hôte

  • 130
  • 100
  • 3
  • 1
  • 1
Souris

Clonalité

  • 160
  • 74
  • 1
Monoclonal

Conjugué

  • 103
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Cet anticorp CD79a est non-conjugé

Application

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone

HM57
  • Épitope

    • 79
    • 15
    • 10
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    • 5
    • 5
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    AA 202-216

    Specificité

    This antibody recognizes an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45 kDa protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells.

    Attributs du produit

    Synonyms: IGA, MB1, B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain,MB-1 membrane glycoprotein, Surface IgM-associated protein, Membrane-boundimmunoglobulin-associated protein

    Purification

    Affinity Chromatography on Protein G

    Immunogène

    Synthetic peptide corresponding to 202-216 amino acid sequence of Human mb-1. Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cellline. Genename: CD79a

    Isotype

    IgG1
  • Indications d'application

    Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: 1/100-1/500, This product requires antigenretrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. Recommended Positive Control: Human tonsilFlow Cytometry: Use 10 μL of 1/50-1/100 diluted CD79a antibody to label 1x10^6 cells in 100μL (Membrane permeabilisation is required). Has been reported to work in Western blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS, 0.09 % Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    Date de péremption

    12 months
  • Antigène

    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

    Autre désignation

    CD79a

    Sujet

    The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin.Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain, IGA, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein

    ID gène

    973

    UniProt

    P11912

    Pathways

    BCR Signaling
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