This antibody recognizes an epitope within the cytoplasmic domain of CD79a.
Réactivité croisée (Details)
Species reactivity (tested):Human, American Bison, Fallow Deer, Canine, Monkey, Pig, Horse, Bovine, Guinea Pig, Rat, Mouse, Rabbit, Chicken.
Attributs du produit
Synonyms: IGA, MB1, B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain,MB-1 membrane glycoprotein, Surface IgM-associated protein, Membrane-boundimmunoglobulin-associated protein
Purification
Affinity Chromatography on Protein G
Immunogène
Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1. Spleencells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line. Genename: CD79a
CD79A
Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Poulet, Cobaye, Cheval, Lapin, Opossum
FACS
Hôte: Souris
Monoclonal
HM57
PE
Indications d'application
Western Blot. Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin sections: This product requires antigen retrieval usingheat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 isrecommended for this purpose. Recommended Positive Control: Human tonsilFlow Cytometry: 1/10 - 1/25, use 10 μL of the suggested working dilution to label 1x10^6cells in 100 μL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.1 mg/mL
Buffer
PBS, pH 7.4, 0.09 % Sodium Azide, 1 % BSA
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Date de péremption
12 months
Antigène
CD79a (CD79A)
(B-cell antigen receptor complex-associated protein alpha chain (CD79A))
CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells. The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin.Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain, IGA, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein