C1QA anticorps

N° du produit ABIN181104

Détail du produit anti-C1QA anticorps

Antigène: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp C1QA est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Specificité: This antibody recognises human complement component 1, q subcomponent (C1q), a 156 kDa secreted protein.

Réactivité croisée (Details): Species reactivity (tested):Human.

Attributs du produit: Synonyms: Complement C1q, Complement 1q

Purification: Affinity Chromatography on Protein A.

Immunogène: Binds globular head domain of C1q, purified from human plasma. Genename: C1QA, C1QB, C1QC

Clone: 3R9-2

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Flow Cytometry. Immunohistochemistry on Frozen Sections: It has been reported that this antibody worksvery well on acetone-fixed, frozen renal biopsies at a dilution of 1/500-1/600. Strongstaining was observed in the glomeruli and in some cases the peritubular capillary(potentially clinically significant). Recommended Positive Control: Kidney tissue from patients with streptococalglomerulonephritis.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Borate Buffered Saline, pH 8.4 containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur C1QA

Antigène: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Autre désignation: C1q A Subunit (C1QA Produits)

Synonymes: anticorps zgc:109903, anticorps C1QA, anticorps AI255395, anticorps C1q, anticorps complement C1q A chain, anticorps complement component 1, q subcomponent, A chain, anticorps complement component 1, q subcomponent, alpha polypeptide, anticorps C1QA, anticorps c1qa, anticorps C1qa

Sujet: C1q associates with proenzymes C1r and C1s to form the calcium-dependent C1 complex, the first component of the serum complement system. C1q is composed of six A, six B-chains and six C-polypeptide chains. Each chain contains a collagen-like region located near the N-terminus and a C-terminal globular region. These regions bind the Fc region of IgM and IgG molecules, initiating the classical pathway of complement activation. C1q deficiency has been associated with lupus erythematosus and glomerulonephritis.Synonyms: Complement 1q, Complement C1q

ID gène: 712

UniProt: P02745

Pathways: Système du Complément