C4BPA anticorps

N° du produit ABIN181109

L’anticorps anti-C4BPA Monoclonal Souris est utilisé pour la détection de C4BPA dans des échantillons de Humain. Il a été validé pour IHC (p) et EIA.

Aperçu rapide pour C4BPA anticorps (ABIN181109)

Antigène: C4BPA (Complement Component 4 Binding Protein, alpha (C4BPA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp C4BPA est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 10-07-14

Détail du produit anti-C4BPA anticorps

Specificité: This antibody recognizes complement component 4 binding protein (C4bp).

Attributs du produit: Synonyms: C4BPA, C4BP, Proline-rich protein, PRP

Purification: Affinity Chromatography on Protein A.

Immunogène: Native Human C4 binding protein. Genename: C4BP

Isotype: IgG2b

Information d'application

Indications d'application: ELISA. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Borate buffered saline, pH 8.4 containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur C4BPA

Antigène: C4BPA (Complement Component 4 Binding Protein, alpha (C4BPA))

Autre désignation: C4b-Binding Protein alpha

Sujet: There are three variants of C4bp, composed of alpha and beta chains. The predominant form is a 570 kDa complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain. C4bp regulates the activation of the classical complement pathway. It is a cofactor to the C3b/C4b inactivator, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b. C4bp also regulates the C4bC2a complex (C3 convertase), accelerating its degradation by dissociating the complement fragment C2a. Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S. C4bp is expressed in the blood serum.Synonyms: C4BP, C4BPA, PRP, Proline-rich protein

ID gène: 722

UniProt: P04003

Pathways: Système du Complément